C (3-6 months) IL-4 knockout mice. Homozygous mutant mice show increased susceptibility to parasitic infection. D3 [129S2/SvPas] 1993年 Max-Planck-Institut for Immunbiologie, Dr. Manfred Kopfらにより開発。 D3 ES細胞由来。東大医科研岩倉研でC57BL/6Jに8世代戻し交配 (兄妹交配13代) (BRC寄託時)。 129S2/SvPas (D3) 1993年 Max-Planck-Institut for Immunbiologie, Dr. Manfred Kopfらにより開発。D3 ES細胞由来。東大医科研岩倉研でC57BL/6Jに8世代戻し交配 (兄妹交配13代) (BRC寄託時)。129S2/SvPas (D3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature, 362(6417):245-248 (1993).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene, SV40 PolyA signal, mouse Il4 genomic DNA <a href='https://brc.riken.jp/mus/pcr04920'>Genotyping protocol -PCR-</a> Developed by Manfred Kopf, Max-Planck-Institut fur Immunbiologie in 1993. The mice were backcrossed to C57BL/6 for at least 8 times by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo. B6-Il4 KO 岩倉 洋一郎 B6.129S2-Il4<tm1Kopf> IL-4遺伝子欠損マウス。寄生虫感染に対して易感染性。 Immunology and Inflammation Research C57BL/6J (亜系統は不明) C(3〜6か月) Yoichiro IWAKURA RBRC04920 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Nature, 362(6417):245-248 (1993).<br>研究成果の公表にあたって謝辞の表明を必要とする。 Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> B6;129S2-Il4<tm1Kopf> B6;129S2-Il4<tm1Kopf> true